Durham University Durham University is one of the best universities in the world with strengths in the arts and humanities, sciences and social sciences.
The Dept. of Biosciences was ranked in the top ten biology departments in the UK for research impact in REF2014. Our basic science underpins applications in all sectors of the bioeconomy, including biotechnology, ecology and agrotechnology. The research programs are grouped into the following areas: plant molecular sciences; biomolecular interactions; Ecology, Evolution and Environment; and Animal Cells and Systems. These groups organize focused seminar series, research days, manage joint research facilities, oversee mentoring, internal peer review, and serve to initiate larger research projects. In addition to our excellent research facilities such as bioimaging, proteomics, metabolomics and genomics, we provide a high quality and supportive environment for our research staff.
Applications are invited for a postdoctoral research associate position in neurobiology with a particular focus on Drosophila neurogenetics. The research project will be undertaken under the supervision of Dr Vincent Croset (Principal Investigator) and funded by UKRI (BBSRC). Nutrition has a significant impact on neural function and behavior. Resolving the interaction between food and the brain is key to preventing or alleviating conditions such as eating disorders, depression or dementia. Nutritional states alter gene expression in the brain, and these alterations may reflect molecular pathways triggering behavioral changes or cellular stress responses induced by the imbalance of key nutrients. This project will use the simple brain of Drosophila melanogaster study the molecular control of behavior dependent on nutritional status. Leveraging recent advances in single-cell transcriptomics, the successful candidate will generate a system-level representation of gene expression correlates of specific nutritional states and assess the behavioral relevance of candidate genes and identified pathways. They will further explore how state-driven transcriptional dynamics change over the lifespan to affect cognitive ability in aged animals.
The successful candidate will join a new team of motivated researchers and will benefit from state-of-the-art equipment within the Department of Biosciences, in particular for fly rearing, behavior or neuroimaging. In addition to research, they will have the opportunity to present their research at national and international conferences and supervise undergraduate and graduate students in the lab, developing their science communication and leadership skills.
This position is fixed term for 1 year initially, renewable for a maximum of 2 additional years as funding is only available for a maximum of 3 years. Successful candidates will ideally be in post before June 1st.st, 2022 (negotiable). All applicants are invited to submit:
- A CV and a cover letter that details your experience, strengths and potential in the requirements set out above;
- A one-page statement outlining your current and future research interests