This is a research support position within the Biology of Inflammation group of the Center for Biology of Inflammation and Cancer Immunology. This group is working on a number of projects relating to the functions of mononuclear phagocytes in cancer and inflammation with the aim of further characterizing the underlying molecular mechanisms and identifying potential diagnostic and therapeutic targets.
The focus of this position will be to support a number of projects involving preclinical models of inflammation-associated cancer and to identify molecular changes in mononuclear phagocytes that contribute to disease pathogenesis. This will involve a number of experimental techniques including imaging, genomics, flow cytometry and transgenic mouse models.
This position will be offered on a 2-year CDD
This is a full time position
This role requires the following;
- Colony management of transgenic mice, flow cytometry analysis of mouse tissue, confocal microscopy analysis of mouse tissue, nucleic acid isolation and preparation of libraries for DNA/RNA sequencing as well as general laboratory tasks .
- Contribute substantially to and prepare data and manuscripts for professional presentation, grant applications and/or publication in peer-reviewed journals in discussion and agreement with supervisor(s).
- Actively participate in and contribute to all project meetings, including symposia, as well as laboratory and divisional research meetings and seminars.
- Be engaged in your own personal career development in science.
The above list of responsibilities may not be exhaustive and the post holder will be required to undertake the duties and responsibilities reasonably expected within the scope and classification of the post.
Knowledge of skills and experience
- Management of colonies of transgenic mice
- flow cytometry
- confocal microscopy
- basic molecular biology/biochemistry
- BSc/MSc/MRes or equivalent
- Thorough knowledge and understanding of a range of immunological, biochemical and molecular biology techniques
- In vivo work experience and colony management of transgenic mice
- Knowledge and understanding of laboratory security requirements and procedures
- Knowledge of computer software for the analysis and presentation of scientific data
- People management skills
- Communication – able to convey instructions, ideas and opinions clearly and concisely, both orally and in writing. Able to communicate with staff at all levels
1. Analysis and Understanding – able to analyze and evaluate evidence; for example in planning, problem solving and decision making
2. Time management – able to plan and use time economically and efficiently